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Find answers to frequently asked questions about chronic pain, diabetic neuropathy, pain management treatments, appointments, and patient care at Pain Relief 1. Frequently Asked Questions Everything you need to know before treatment. Prolo Dextrose Therapy 1. What is dextrose prolotherapy? Dextrose prolotherapy is a regenerative injection treatment that uses a concentrated sugar (dextrose) solution to stimulate the body's natural healing response. The solution is injected into injured or weakened ligaments, tendons, or joint attachments with the goal of promoting tissue repair and improving stability. Unlike corticosteroid injections, prolotherapy is intended to encourage healing rather than simply reduce inflammation. It is commonly used for selected patients with chronic musculoskeletal pain that has not improved with conservative treatment. 2. What conditions can dextrose prolotherapy treat? Dextrose prolotherapy may be helpful for selected patients with chronic musculoskeletal conditions, including: •Ligament laxity and joint instability •Chronic tendon injuries (tendinopathy) •Knee osteoarthritis •Sacroiliac (SI) joint pain •Chronic low back pain related to ligament injury •Shoulder instability •Tennis or golfer's elbow •Plantar fasciitis •Certain sports injuries Not every condition responds equally well, and an accurate diagnosis is essential before treatment. 3. Is prolotherapy painful, and how many treatments will I need? Because prolotherapy involves injections into injured tissues, some temporary discomfort during and after the procedure is expected. Most patients experience soreness for a few days, which gradually improves. Treatment is usually performed as a series of 3 to 6 sessions, spaced several weeks apart, although the exact number depends on the condition being treated, the severity of the injury, and your response to therapy. Many patients notice gradual improvement over several weeks to months as healing progresses. 4. Is prolotherapy supported by scientific research? Research on prolotherapy has grown over the past two decades. Clinical studies suggest that dextrose prolotherapy may improve pain and function for certain conditions, particularly some forms of chronic tendon disorders, knee osteoarthritis, and ligament-related pain. However, evidence varies depending on the specific condition being treated, and prolotherapy is not considered the standard treatment for every musculoskeletal disorder. Your physician will discuss whether current evidence supports its use for your diagnosis and whether other treatment options may be more appropriate. 5. How is prolotherapy different from PRP or stem cell treatments? All three treatments aim to support healing, but they differ in what is injected. •Dextrose prolotherapy uses a sterile dextrose solution to stimulate the body's natural healing response. •Platelet-Rich Plasma (PRP) uses a concentration of your own platelets, which contain growth factors involved in tissue repair. •Bone Marrow Aspirate Concentrate (BMAC) contains cells and biologically active components obtained from your own bone marrow. The most appropriate treatment depends on your diagnosis, the severity of tissue damage, your overall health, previous treatments, and your treatment goals. During your evaluation, we will recommend the option that best fits your individual situation rather than using the same treatment for every patient. General Regenerative Therapy 1. What is regenerative musculoskeletal (MSK) medicine? Regenerative musculoskeletal (MSK) medicine is a field of medicine focused on helping the body repair injured muscles, tendons, ligaments, joints, and other connective tissues. Rather than simply masking pain, regenerative treatments aim to support the body's natural healing processes when appropriate. Depending on the diagnosis, treatment options may include shockwave therapy, prolotherapy, platelet-rich plasma (PRP), bone marrow aspirate concentrate (BMAC), physical rehabilitation, and other evidence-based therapies. Not every patient is a candidate, and treatment recommendations are individualized after a comprehensive evaluation. 2. What conditions can regenerative MSK treatments help? Regenerative treatments may be appropriate for selected patients with chronic musculoskeletal conditions such as: •Arthritis of certain joints •Tendon injuries (tendinopathy) •Ligament sprains and instability •Plantar fasciitis •Rotator cuff disorders •Tennis and golfer's elbow •Knee pain •Hip pain •Certain spine-related conditions •Sports injuries and overuse injuries A careful diagnosis is essential because different conditions respond to different treatments. 3. Are regenerative treatments a replacement for surgery? Not always. Regenerative medicine is not intended to replace surgery in every situation, but it may offer a non-surgical option for carefully selected patients. Some individuals improve enough to postpone or avoid surgery, while others may still benefit from an operation if structural damage is severe. Our goal is to recommend the treatment that offers the greatest likelihood of improving pain, function, and quality of life—not simply the newest treatment available. 4. How do I know if I am a candidate for regenerative treatment? The first step is a comprehensive medical evaluation. We review your medical history, symptoms, physical examination, imaging studies (such as X-rays or MRI), previous treatments, and your personal goals. Factors such as the type of injury, severity of tissue damage, overall health, activity level, and expectations all help determine whether regenerative treatment is appropriate. Some patients benefit most from regenerative therapies, while others may be better served with physical therapy, medications, interventional procedures, or surgery. 5. How long does it take to see results from regenerative treatments? Healing takes time. Unlike treatments that temporarily numb pain, regenerative therapies are designed to support the body's natural repair process. Many patients begin noticing improvement over several weeks, while others continue to improve over two to six months, depending on the condition and the treatment used. Recovery times vary, and no treatment can guarantee a specific outcome. Your physician will discuss what you can realistically expect based on your diagnosis. Ketamine Therapy for Depression 1. What are ketamine infusions for depression? Ketamine infusion therapy is an intravenous (IV) treatment that may help adults with treatment-resistant depression, meaning depression that has not improved adequately despite appropriate treatment with antidepressant medications, psychotherapy, or both. Unlike traditional antidepressants, which often take several weeks to become effective, ketamine works through different pathways in the brain, including the N-methyl-D-aspartate (NMDA) receptor. Some patients experience improvement in depressive symptoms within hours to days, although individual responses vary. Treatment is provided under close medical supervision with continuous monitoring. 2. Who is a candidate for ketamine infusion therapy? Ketamine infusion therapy may be considered for adults with: •Treatment-resistant depression •Major depressive disorder that has not responded adequately to conventional treatments •Depression associated with significant functional impairment •Certain patients with severe depressive symptoms, after careful evaluation Not everyone is an appropriate candidate. Before treatment, we perform a comprehensive medical and psychiatric assessment, review your medications and medical history, and discuss the potential benefits, risks, and alternative treatment options. 3. What happens during a ketamine infusion? During the infusion, ketamine is administered slowly through an intravenous (IV) line while your blood pressure, heart rate, oxygen level, and overall condition are continuously monitored. A typical treatment lasts about 40 to 60 minutes, followed by a recovery period before you are discharged home. Because ketamine may temporarily affect judgment, coordination, or vision, you should arrange for someone to drive you home after each treatment. Most patients receive an initial series of infusions, after which your physician will determine whether maintenance treatments are appropriate based on your response. 5. How soon does ketamine work, and how long does it last? Some patients notice improvement in depressive symptoms within hours to several days, while others require multiple treatments before experiencing meaningful benefit. The duration of improvement varies from person to person. Some individuals benefit for weeks or months after an initial treatment series, while others may require periodic maintenance infusions. Ketamine therapy is generally used as part of a comprehensive treatment plan that may also include ongoing psychiatric care, psychotherapy, and other appropriate treatments. 6. Is ketamine FDA-approved for depression? Intravenous (IV) ketamine itself is not currently FDA-approved for the treatment of depression. Ketamine has been FDA-approved for many years as an anesthetic, but its use for depression is considered "off-label." Off-label prescribing is a common and accepted medical practice when supported by scientific evidence and clinical judgment. Numerous clinical studies have demonstrated that ketamine may provide rapid improvement in depressive symptoms for carefully selected patients with treatment-resistant depression. Your physician will discuss whether ketamine therapy is appropriate for your individual situation, as well as its potential benefits, risks, and alternatives. 7. What is the difference between ketamine infusions and Spravato®? Both ketamine and Spravato® (esketamine) are used to treat certain patients with treatment-resistant depression, but they are different medications delivered in different ways. Ketamine infusions: •Administered through an intravenous (IV) line. •Use ketamine, a medication that contains two mirror-image forms (R- and S-ketamine). •The dose can be individualized by your physician. •Used off-label for depression. Spravato® (esketamine): •Is an FDA-approved prescription nasal spray for specific patients with treatment-resistant depression and certain cases of major depression with acute suicidal thoughts or behavior. •Contains only the S-form (esketamine). •Must be administered in a certified healthcare facility under the FDA's Risk Evaluation and Mitigation Strategy (REMS) program. •Is prescribed together with an oral antidepressant. Both treatments require medical monitoring, and your physician can help determine which option may be most appropriate based on your diagnosis, medical history, treatment goals, and insurance coverage. 4. Is ketamine infusion therapy safe? When administered in an appropriate medical setting with careful patient selection and monitoring, ketamine infusion therapy has an established safety profile. Temporary side effects may include: •Feeling detached or "dream-like" •Dizziness •Nausea •Blurred vision •Sleepiness •Temporary increases in blood pressure or heart rate These effects usually resolve shortly after the infusion is completed. Before recommending treatment, we review your medical and psychiatric history to determine whether ketamine therapy is appropriate for you. 8. Does insurance cover ketamine infusions for depression? Insurance coverage for ketamine infusion therapy varies considerably. Because IV ketamine is used off-label for depression, many insurance plans do not routinely cover the cost of treatment. Some plans may reimburse portions of the medical evaluation, monitoring, or infusion services, while others may not provide coverage. In contrast, Spravato® (esketamine) is FDA-approved for certain forms of depression and may be covered by some insurance plans when specific medical criteria are met. Our staff can help explain expected costs, discuss payment options, and determine whether any portion of your treatment may be eligible for insurance reimbursement. We encourage patients to contact their insurance carrier for information about their specific benefits. Ketamine & Lidocaine IV Therapy 1. What is a lidocaine infusion for neuropathic pain? A lidocaine infusion is an intravenous (IV) treatment used to help relieve certain types of chronic neuropathic (nerve) pain. Lidocaine is a local anesthetic that, when administered intravenously in carefully controlled doses, can reduce abnormal pain signaling by stabilizing overactive nerve cells. Unlike opioid medications, lidocaine does not work by blocking pain perception. Instead, it targets the nerve pathways involved in neuropathic pain. Treatment is performed under continuous medical supervision with monitoring throughout the infusion. 2. What conditions can lidocaine infusions treat? Lidocaine infusions may be beneficial for selected patients with chronic neuropathic pain, including: •Painful diabetic neuropathy •Peripheral neuropathy •Postherpetic neuralgia (pain after shingles) •Complex Regional Pain Syndrome (CRPS) •Small fiber neuropathy •Certain nerve injuries •Other chronic neuropathic pain conditions that have not responded adequately to conventional treatments Your physician will determine whether lidocaine infusion therapy is appropriate based on your diagnosis, medical history, and previous treatments. 3. What happens during a lidocaine infusion? During treatment, lidocaine is administered slowly through an intravenous (IV) line while your heart rate, blood pressure, oxygen level, and overall condition are continuously monitored. Most infusions last 30 to 90 minutes, depending on the treatment protocol. Many patients return home shortly afterward, although someone else may need to drive you home depending on your response to treatment and your physician's recommendations. 4. Is lidocaine infusion therapy safe? When administered by experienced medical professionals using appropriate monitoring and patient selection, intravenous lidocaine has an established safety profile. Some patients experience temporary side effects such as: •Lightheadedness •Dizziness •Ringing in the ears •Metallic taste •Mild numbness around the mouth •Nausea •Temporary changes in heart rhythm or blood pressure (uncommon with proper monitoring) Before treatment, we review your medical history, medications, and, when appropriate, your heart health to help ensure that lidocaine therapy is safe for you. 5. How many lidocaine infusions will I need? The number of treatments varies depending on your condition and your response to therapy. Some patients experience meaningful relief after a single infusion, while others benefit from an initial series of treatments followed by occasional maintenance infusions. Relief may last from several days to several weeks or longer, depending on the individual and the underlying cause of the neuropathic pain. Your treatment plan will be tailored to your specific condition and adjusted based on your progress. These FAQs are also optimized for common Google searches such as: •lidocaine infusion for neuropathy •IV lidocaine for diabetic neuropathy •lidocaine infusion for nerve pain •treatment for painful neuropathy •non-opioid treatment for neuropathic pain •IV lidocaine side effects •how long does a lidocaine infusion last •lidocaine infusion near me These search terms tend to attract patients actively seeking alternatives to oral medications or opioids. Still Have Questions? We're here to help. Our team is ready to answer your questions and help you determine if Prolo Dextrose Therapy is right for you. SCHEDULE YOUR CONSULTATION or Phone CALL US TODAY (920) 939-6015

Learn about Pain Relief 1 and how we help patients with back pain, feet pain, neck pain, joint pain, nerve pain, arthritis, and chronic pain through personalized treatment plans. Visit Our Clinic Clinic Hours Monday & Thursday: 08:30 AM – 5:00 PM Tuesday: 08:30 AM – 12:00 PM Wednesday & Friday: Procedure & Surgery Saturday & Sunday: Closed Location 526 W Wisconsin Ave, Appleton, WI 54911, United States (920) 939-6015 Mail info@painrelief1.net Get Directions REQUEST AN APPOINTMENT Book Your Consultation. Send us your details and our team will contact you to schedule your visit with Dr. Albala. Contact us First name* Last name Email* Write a message Phone* Submit

KETAMINE THERAPY FOR DEPRESSION A New Path Toward Hope and Healing. Ketamine Therapy offers a new path forward for individuals struggling with depression, especially when traditional treatments haven't provided relief. Ketamine works differently than conventional antidepressants, targeting brain pathways involved in mood regulation to help reset and restore balance. Many patients experience rapid improvement in symptoms, often within hours or days. Our safe, medically supervised infusion therapy is designed to provide relief, restore hope, and support long-term mental wellness. SCHEDULE A CONSULTATION How Ketamine Therapy Can Help Rapid Relief Improvement in symptoms often within hours or days. Mood Balance Targets brain pathways involved in mood regulation. Restores Hope Helps break the cycle of depression and emotional fatigue. Medically Supervised Safe, closely monitored infusions in a comfortable setting. Long-Term Wellness Supports lasting improvement and better quality of life. Questions About Ketamine Therapy? Explore our FAQ page to learn more about treatment process, safety, and what to expect. VIEW FAQS You Don't Have to Face Depression Alone. We're here to help you find relief and rediscover life. BOOK AN APPOINTMENT CONTACT US

Explore comprehensive pain management services at Pain Relief Wisconsin, including diabetic neuropathy treatment, spine care, joint pain management, regenerative medicine, ketamine therapy, and advanced interventional procedures. WHAT WE TREAT Our Services Personalized, evidence-based care for lasting relief. We treat the root cause - not just the symptoms. FEATURED TREATMENT Regenexx Procedures Procedures using Regenexx® injectates provide non-surgical treatment options for those suffering from pain related to osteoarthritis, joint injuries, spine pain, overuse conditions, and common sports injuries. Learn More Prolo Dextrose Therapy Prolo Dextrose Therapy is a regenerative injection treatment that uses a precise dextrose solution to stimulate your body's natural healing response. Learn More General Regenerative Therapy General Regenerative Therapy focuses on stimulating your body's innate ability to heal, restore, and rejuvenate damaged tissues. Learn More Ketamine Therapy for Depression Ketamine Therapy offers a new path forward for individuals struggling with depression, especially when traditional treatments haven't provided relief. Learn More Ketamine & Lidocaine IV Therapy Ketamine and Lidocaine IV Therapy is an advanced treatment option for neuropathic pain—especially when other therapies haven't worked. Learn More Not Sure Which Treatment Is Right for You? Book an Appointment Schedule a consultation with Dr. Albala to talk through your goals and options.

Learn about Maurizio Z. Albala, MD, a board-certified pain management specialist dedicated to treating chronic pain, neuropathy, spine, and joint conditions with personalized, evidence-based care. ABOUT DR. ALBALA Experience. Expertise. A personalized approach to care. Maurizio Z. Albala, MD is a board-certified anesthesiologist and pain medicine physician in Appleton, Wisconsin, with expertise in interventional pain management, regenerative medicine, and musculoskeletal care. Book an Appointment A comprehensive approach to pain care. TRAINING & EXPERIENCE Pain Medicine Fellowship Tufts Medical Center Adult Cardiothoracic Anesthesiology Fellowship Massachusetts General Hospital Anesthesiology Residency Brigham and Women’s Hospital Fellowship in Orthopedic Medicine Paris Senior Attending Physician Italy Dr. Albala specializes in the diagnosis and treatment of spine pain, neuropathic pain, and other chronic pain conditions. His clinical expertise includes interventional pain management, image-guided spine procedures, neuromodulation (spinal cord stimulation), ketamine therapy, ultrasound-guided diagnostics and injections, and regenerative medicine treatments such as platelet-rich plasma (PRP) and other biologic therapies. He treats a wide range of conditions including lumbar spondylosis, radiculopathy, facet joint pain, sacroiliac joint dysfunction, peripheral nerve pain, and musculoskeletal injuries. Dr. Albala’s approach emphasizes accurate diagnosis, minimally invasive treatments, functional restoration, and personalized care tailored to each patient’s goals. Dr. Albala brings a unique international perspective to his practice. He served as a senior attending physician in Italy, with experience in anesthesiology, intensive care, and cancer pain management. He completed a fellowship in orthopedic medicine in Paris, and subsequently pursued advanced training in the United States, including a pain medicine fellowship at Tufts Medical Center, an adult cardiothoracic anesthesiology fellowship at Massachusetts General Hospital, and an anesthesiology residency at Brigham and Women’s Hospital. TAKE THE NEXT STEP Explore What’s Possible. Book an Appointment Learn more about our approach to regenerative musculoskeletal care.

Learn about painful diabetic neuropathy, its symptoms, causes, and advanced treatment options at Pain Relief Wisconsin to help reduce pain and improve quality of life. NATURAL HEALING. LASTING RELIEF Prolo Dextrose Therapy Prolo Dextrose Therapy is a regenerative injection treatment that uses a precise dextrose solution to stimulate your body's natural healing response. By gently irritating weakened ligaments, tendons, and joints, it encourages the growth of stronger, healthier tissue and improves stability and function. This minimally invasive therapy is a safe, cost-effective option for chronic musculoskeletal pain caused by injuries, overuse, or arthritis. It aims to address the root cause of pain—not just mask it—helping you move better and live better. SCHEDULE A CONSULTATION How Prolo Dextrose Therapy Works 1. Precise Injection A precise dextrose solution is injected into weakened ligaments, tendons, or joints. 2. Mild Irritation The solution gently irritates the area, triggering your body's natural healing response. 3. Tissue Regeneration New collagen and healthy tissue grow stronger, improving stability and function. 4. Long-Term Relief Reduced pain, improved mobility, and better quality of life—naturally and safely. WHO CAN BENEFIT? Is Prolo Dextrose Therapy Right for You? Prolo Dextrose Therapy may help if you are experiencing: Chronic joint, tendon, or ligament pain Pain from injuries or overuse Osteoarthritis or degenerative joint changes Tendonitis or ligament laxity Back, neck, knee, or shoulder pain Recurring pain despite other treatments Minimally Invasive Quick, in-office treatment with minimal downtime. Cost-Effective A safe, affordable option for long-term relief. Natural Healing Works with your body to heal and restore. Long-Lasting Results Targets the root cause for sustainable relief. Have questions about Prolo Dextrose Therapy? Visit our FAQ page to learn more. VIEW FAQS

GENERAL REGENERATIVE THERAPY Healing Naturally. Improving Function. Improving Lives. General Regenerative Therapy focuses on stimulating your body's innate ability to heal, restore, and rejuvenate damaged tissues. Using advanced, minimally invasive techniques, we target the source of pain and dysfunction to promote long-term recovery and improved quality of life. Our personalized approach may include therapies such as PRP, prolotherapy, and other biologic treatments designed to support natural healing, reduce inflammation, and improve function—without relying on surgery or long-term medications. SCHEDULE A CONSULTATION CONDITIONS WE COMMONLY TREAT Support for Many Musculoskeletal Conditions Joint Pain & Osteoarthritis Chronic Back & Neck pain Sports & Soft Tissue Tendon & Ligament Injuries Chronic Pain Conditions Overall Wellness & Rejuvenation Still Exploring Your Treatment Options? Visit our FAQ page to learn more about treatments, recovery, and what to expect. VIEW FAQS Ready to Take the Next Step? Our team is here to help you heal naturally and live life to the fullest. BOOK AN APPOINTMENT CONTACT US

Explore our services and get in touch Our Services 01. Custom Project This service is designed to address your unique requirements with a tailored approach. Our team will collaborate closely with you to understand your specific needs and deliver a bespoke solution. Expect a detailed plan and execution that perfectly matches your vision. We ensure every aspect is covered for optimal results. Show more 02. Personal Solution Planning Get a personalized strategy designed specifically for your situation. We focus on understanding your individual goals and challenges to develop a clear roadmap for success. This service provides actionable steps that are easy to follow. Achieve your objectives with a plan that's made just for you. Show more 03. Expert Guidance Package Leverage our expertise with a comprehensive package of insights and advice. This service offers access to industry knowledge and best practices to help you navigate complex decisions. Receive clear, informed recommendations to move forward confidently. Empower your journey with professional support. Show more

Get back to the activities you love, without surgery. Learn More About Our Regenerative Orthopedic Procedures Using Regenexx Injectates Complete the Candidate Form Regenexx – The Trusted Alternative to Orthopedic Surgery Reduce Pain and Improve Function with Procedures Using Regenexx Injectates Procedures using Regenexx® injectates provide non-surgical treatment options for those suffering from pain related to osteoarthritis, joint injuries, spine pain, overuse conditions, and common sports injuries. These medical procedures are only performed by highly-skilled physicians trained specifically in Interventional Orthopedics, and are used to help reduce pain and improve function. These procedures have helped thousands of patients improve their quality of life, return to the activities they enjoy, and avoid the need for surgery or joint replacement.* Physicians in the licensed Regenexx network represent a very selective, highly-skilled, interventional orthopedics network that is 100% focused on orthopedic conditions. All physicians are musculoskeletal experts with extensive training and experience in the diagnosis and treatment of musculoskeletal conditions, as well as complex, image-guided injections of your body's own healing agents to treat orthopedic issues. Regenexx provider patient outcomes are tracked in a registry and with that information, we provide transparent outcome data (below) for those who may be considering this treatment option. Want to find out if you are a Regenexx Candidate? Complete the Candidate Form 185,244 More than 185,244 highly specific image-guided procedures using Regenexx injectates have been performed since Regenexx pioneered the field of interventional orthopedics, using your body's own cells to treat common orthopedic problems in 2005. Regenexx is a world leader in the field of orthopedic regenerative medicine based on scientific publications and is arguably the world’s most advanced platform for in-office interventional orthopedics. 44% The published research on procedures using Regenexx injectates accounts for approximately 44% of the world’s research on the use of bone marrow concentrate for orthopedic conditions (cumulative n of patients published & treated with bone marrow concentrate as of 1/1/2019) How Procedures Using Regenexx Injectates Work Regenexx SD Injectate · Bone Marrow Concentrate Regenexx SD injectate is Bone Marrow Concentrate, which contains stem cells. These repair cells from your own body live inside all of us in various tissues, poised to leap into action to repair damage as it occurs. As we age or have big injuries, we may not be able to recruit enough of these cells to the site to fully repair the area. The procedure using Regenexx SD injectate helps overcome this problem by harvesting Bone Marrow from an area of the back of the hip that contains a dense population of these important cells and then concentrating those cells before precisely injecting them into the injured area using advanced imaging guidance. The goal of the procedure is to reduce pain and improve function by promoting the body's own ability to heal naturally. This Patented Bone Marrow Concentrate Protocol can be used for a wide range of orthopedic conditions. Your doctor will evaluate your condition and your imaging to determine whether a bone marrow concentrate or platelet-based treatment is the best option for your orthopedic condition. Regenexx SCP Injectate · Super Concentrated Platelet Rich Plasma & Platelet Lysate Procedures Platelet Rich Plasma (PRP) and Platelet Lysate are Platelet procedures that contain healing growth factors from your own blood that promote your body’s natural ability to repair itself. The use of PRP to treat joint, tendon, ligament, and muscle injuries is becoming well known, thanks to exposure from professional athletes. Platelet injections have a stimulating effect on the repair cells within the targeted area, making those cells work harder to perform their natural job of healing the body. Like all procedures using Regenexx injectates, this procedure is performed with high-level image guidance to ensure the most accurate placements of cells into the desired area. Procedures using Regenexx SCP injectate are more concentrated and purer than PRP created by the typical machines used at most regenerative medicine clinics. This increases its ability to stimulate the body's natural healing response. Platelet procedures are commonly used for soft tissue injuries, mild arthritis, spine conditions, and around nerves. Regenexx Provider Patient Outcome Data Regenexx is unique in that it maintains an active patient registry that continually prompts patients to update their progress or side effects post-procedure using Regenexx injectates. As a result, we keep records on tens of thousands of procedures performed by physicians in the licensed Regenexx network in our outcomes database. Regenexx is the only company that has tracked an orthopedic patient population of this size, who were treated with bone marrow concentrate. In our effort to be completely transparent with potential patients, we make these results available through our website. You can see for yourself how many procedures we’re tracking and the results patients have reported. With Regenexx, you have the tools you need to make an informed decision about what treatment option is right for you. *DISCLAIMER: Like all medical procedures, procedures using Regenexx lab processes have a success and failure rate. Patient reviews and testimonials on this site should not be interpreted as a statement on the effectiveness of treatments for anyone else. FREE WEBINAR Regenexx Overview Webinar Learn about non-surgical orthopedic procedures using Regenexx injectates for joint injuries, arthritis, and spine pain. View Webinar Download eBooks Make an Appointment Call (920) 939-6015 for more info or to make an appointment Complete the Candidate Form

Pain Relief 1 provides advanced pain management, diabetic neuropathy treatment, regenerative medicine, ketamine infusion therapy, and non-surgical chronic pain care in Appleton, Wisconsin. Personalized treatments focused on restoring mobility, reducing pain, and improving quality of life. UNDER CONSTRUCTION • NEW WEBSITE COMING SOON • REGENERATIVE MEDICINE Improve Function. Renew Movement. Advanced regenerative musculoskeletal care, guided by science and personalized to you. Book an Appointment THE SCIENCE OF REGENERATIVE MEDICINE A Biological Approach to Musculoskeletal Care. We use advanced regenerative approaches informed by the biology of tissues, joints, and movement. Explore Our Approach HEALTHY TISSUES. BETTER MOVEMENT. Targeting the Biology Behind Movement. Our approach considers the biological health of joints, tendons, ligaments, and other musculoskeletal tissues while developing personalized treatment strategies that support function and mobility. Explore Treatments The Body Is More Than Its Symptoms Understanding the biology behind movement can help inform a more personalized approach to musculoskeletal care. OUR APPROACH Personalized Regenerative Care. Joints Cartilage Tendons Musculoskeletal Conditions Ligaments Biological Tissue Health MEET OUR PHYSICIAN Maurizio Z. Albala, MD Dr. Albala is a board-certified pain management specialist with extensive experience in interventional and regenerative medicine. His approach combines medical expertise, advanced techniques and personalized care. Meet Dr. Albala OUR LOCATION Advanced Care. Personal Setting. Our clinic in Appleton, Wisconsin provides a comfortable, professional environment for personalized regenerative care. Visit Our Location TAKE THE NEXT STEP Explore What's Possible. Book an Appointment Learn more about our approach to regenerative musculoskeletal care.

KETAMINE & LIDOCAINE IV THERAPY Advance Relief for Neuropathic Pain Ketamine and Lidocaine IV Therapy is an advanced treatment option for neuropathic pain—especially when other therapies haven't worked. These medications work together to calm overactive nerves, reduce pain signals, and help improve function and quality of life. This therapy is especially helpful for conditions like diabetic neuropathy, post-surgical pain, complex regional pain syndrome (CRPS), and nerve-related pain. Treatments are administered in a safe, monitored setting with a focus on relief, recovery, and renewed hope. SCHEDULE A CONSULTATION HOW THIS THERAPY CAN HELP Targets Nerve Pain Calms overactive nerves and reduces pain signals. Dual-Action Relief Ketamine and Lidocaine work together for enhanced relief. Improves Function Helps restore mobility, comfort, and daily function. Safe & Monitored IV therapy administered in a safe, closely monitored setting. Better Quality of Life Supports long-term relief and overall well-being. Questions About Ketamine Therapy? Explore our FAQ page to learn more about treatment process, safety, and what to expect. VIEW FAQS Take the Next Step Toward Relief. We're here to help you regain comfort and get back to living your life. BOOK AN APPOINTMENT CONTACT US